Preparation method of (1R,3S,4S)-3-(6-bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester_ Kain Industrial Additives

Background and overview[1] (1R,3S,4S)-3-(6-bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester can Harvoni is used as an intermediate in pharmaceutical synthesis, such as the preparation of a two-combination combination of the new antiviral NS5A inhibitor Ledipasvir (GS5885) and the NS5B blocker Sofosbuvir. It is a blockbuster hepatitis C treatment drug approved by Gilead in December 2013. Harvoni is the first all-oral anti-HCV regimen approved for the treatment of genotype 1…

(1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester ,1256387-74-2

(1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester ,1256387-74-2

  Post Date: Jan 17,2022   Expiry Date: Jan 17,2023   Detailed Description: Cas No. :1256387-74-2 Quantity: 200Kilograms Specs:enterprise standard Payment Method: T/T advance Product name: (1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl esterCAS #: 1256387-74-2  molecular formula; C18H22BrN3O2   CAS Registry Number: 1256387-74-2   Synonyms: ;1(R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1] heptane-2-carboxylic acid 1,1-dimethylethyl ester;Ledipasvir Intermediates;Ledipasvir Intermediate;(1R,3S,4S)-tert-butyl 3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1] heptane-2-carboxylate;3-(6-Bromo-1H-benzoimidazol-2-yl)-2-aza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester;(1r,3s,4s)-3-(6-bromo-1h-benzimidazol-2-yl)-2-azabicyclo(2.2.1)heptane-2-carboxylicacid 1,1-dimethyl ethylester;Tert-butyl (1R,3S,4S)-3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate;(1R,3S,4S)-tert-butyl 3-(6-broMo-1Hbenzo[d]iMidazol-2-yl)-2-azabicyclo[2,2,1] heptanes-2-carboxylate;(1R,3S,4S)-tert-butyl-3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2,2,1]heptane-2-carboxylate;2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)-;

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

  Post Date: Jan 11,2022   Expiry Date: Jan 11,2023   Detailed Description: Cas No. :361440-67-7 Specs:25kg/Drum Payment Method: T/T Product Name:(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester CAS #: 361440-67-7Molecular Formula: C11H18N2O3 Molecular Weight: 226.27 Appearance White to off-white powderWater(KF) Not more than1.0%Purity (HPLC) Not less than 98.0%   CAS Registry Number: 361440-67-7   Synonyms: ;Saxagliptin Intermediate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)-;(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-3-aminocarbonyl-2-azabicyclo[3.1.0]hexane-2-carboxylic acid, 1,1-dimethylethyl ester;(1S,3S,5S)-3-(Amino carbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate;(1s,3s,5s)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylic…

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(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester 361440-67-7

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester 361440-67-7

  Post Date: Dec 28,2021   Expiry Date: Dec 28,2022   Detailed Description: Cas No. :361440-67-7 Quantity: 100Kilograms Specs:Purity: 98% Molecular Formula: C11H18N2O3Molecular Weight: 226.27Density: 1.228   CAS Registry Number: 361440-67-7   Synonyms: ;Saxagliptin Intermediate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)-;(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-3-aminocarbonyl-2-azabicyclo[3.1.0]hexane-2-carboxylic acid, 1,1-dimethylethyl ester;(1S,3S,5S)-3-(Amino carbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate;(1s,3s,5s)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylic acid tert-butyl;   Molecular Formula: C11H18N2O3   Molecular Weight: 226.27   Molecular Structure:

(1S,3S,5R,6S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl acetate acetate

(1S,3S,5R,6S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl acetate acetate

  Post Date: Dec 28,2021   Expiry Date: Jun 26,2022   Detailed Description: Cas No. :85644-59-3 purity 98%+   CAS Registry Number: 85644-59-3

(3S,4aS,8aR)-N-tert-Butyldecahydroisoquinoline-3-carboxamide

(3S,4aS,8aR)-N-tert-Butyldecahydroisoquinoline-3-carboxamide

  Post Date: Dec 08,2021   Expiry Date: Jun 06,2022   Detailed Description: Cas No. :136465-81-1   CAS Registry Number: 136465-81-1   Synonyms: ;[(3S)-4-Azabicyclo[4.4.0]dec-3-yl]-N-(tert-butyl)carboxamide;(3S,4aS,8aR)-N-tert-Butyldecahydroisoquinoline-3-carboxamide;n-tert-butyl decahydroisoquinoline-3(s)-carboxamide;(3S,4aS,8aS)-N-tert-butyldecahydroisoquinoline-3-carboxamide;(3S,4aS,8aS)-3-(tert-butylcarbamoyl)decahydroisoquinolinium;(3S,4aS,8aR)-3-(tert-butylcarbamoyl)decahydroisoquinolinium;   Molecular Formula: C14H27N2O   Molecular Weight: 239.3764   Molecular Structure:   Safety Description: S24/25:;

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester 361440-67-7

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester 361440-67-7

  Post Date: Dec 07,2021   Expiry Date: Dec 07,2022   Detailed Description: Cas No. :361440-67-7 Quantity: 100Kilograms Specs:Purity: 98% Molecular Formula: C11H18N2O3Molecular Weight: 226.27Density: 1.228   CAS Registry Number: 361440-67-7   Synonyms: ;Saxagliptin Intermediate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)-;(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-3-aminocarbonyl-2-azabicyclo[3.1.0]hexane-2-carboxylic acid, 1,1-dimethylethyl ester;(1S,3S,5S)-3-(Amino carbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate;(1s,3s,5s)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylic acid tert-butyl;   Molecular Formula: C11H18N2O3   Molecular Weight: 226.27   Molecular Structure:

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

  Post Date: Nov 30,2021   Expiry Date: Nov 30,2022   Detailed Description: Cas No. :361440-67-7 Specs:25kg/Drum Payment Method: T/T Product Name:(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester CAS #: 361440-67-7Molecular Formula: C11H18N2O3 Molecular Weight: 226.27 Appearance White to off-white powderWater(KF) Not more than1.0%Purity (HPLC) Not less than 98.0%   CAS Registry Number: 361440-67-7   Synonyms: ;Saxagliptin Intermediate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)-;(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-3-aminocarbonyl-2-azabicyclo[3.1.0]hexane-2-carboxylic acid, 1,1-dimethylethyl ester;(1S,3S,5S)-3-(Amino carbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester;(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate;(1s,3s,5s)-3-(aminocarbonyl)-2-azabicyclo(3.1.0)hexane-2-carboxylic…

(1S,3S,5R,6S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl acetate acetate

(1S,3S,5R,6S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl acetate acetate

  Post Date: Nov 30,2021   Expiry Date: May 29,2022   Detailed Description: Cas No. :85644-59-3 purity 98%+   CAS Registry Number: 85644-59-3

(1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester ,1256387-74-2

(1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl ester ,1256387-74-2

  Post Date: Nov 24,2021   Expiry Date: Nov 24,2022   Detailed Description: Cas No. :1256387-74-2 Quantity: 200Kilograms Specs:enterprise standard Payment Method: T/T advance Product name: (1R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-dimethylethyl esterCAS #: 1256387-74-2  molecular formula; C18H22BrN3O2   CAS Registry Number: 1256387-74-2   Synonyms: ;1(R,3S,4S)-3-(6-Bromo-1H-benzimidazol-2-yl)-2-azabicyclo[2.2.1] heptane-2-carboxylic acid 1,1-dimethylethyl ester;Ledipasvir Intermediates;Ledipasvir Intermediate;(1R,3S,4S)-tert-butyl 3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1] heptane-2-carboxylate;3-(6-Bromo-1H-benzoimidazol-2-yl)-2-aza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester;(1r,3s,4s)-3-(6-bromo-1h-benzimidazol-2-yl)-2-azabicyclo(2.2.1)heptane-2-carboxylicacid 1,1-dimethyl ethylester;Tert-butyl (1R,3S,4S)-3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate;(1R,3S,4S)-tert-butyl 3-(6-broMo-1Hbenzo[d]iMidazol-2-yl)-2-azabicyclo[2,2,1] heptanes-2-carboxylate;(1R,3S,4S)-tert-butyl-3-(6-bromo-1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2,2,1]heptane-2-carboxylate;2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)-;

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