Preparation of 3,4,5-trimethoxybromobenzene_Kain Industrial Additive
Background and overview[1] 3,4,5-Trimethoxybromobenzene can be used as a pharmaceutical synthesis intermediate. It can be prepared by the reaction of 5-bromo-1,2,3 trihydroxybenzene and dimethyl sulfate, or it can also be prepared from 4-bromo-2 , 6-dimethoxyphenol was prepared as the reaction raw material. Preparation[1-2] Option 1, Cool the mixture of 5-bromo-1,2,3 trihydroxybenzene (1.3g, 5.63mmol), 1M NaOH (14mL) and dimethyl sulfate (800μL, add 16.89mmol) to 10°C. The mixture…
Production method and device of 2,4,5-trichloroaniline_Kain Industrial Additive
Background and overview[1] 2,4,5-Trichloroaniline is a poison that can spontaneously ignite. It also has the function of supporting combustion and can also be used as a dye intermediate. It is slightly soluble in petroleum ether and easily soluble in ethanol and carbon disulfide. During the production and preparation process, it needs to be in a cool and ventilated environment, and workers must wear protective clothing to…
Preparation of 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one_Kain Industrial Additive
Background and Overview[1] 3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. Benazepril hydrochloride is a first-line antihypertensive drug recommended by the World Health Organization. It is a chiral drug with good clinical efficacy, high safety and few side effects among the current international angiotensin-converting enzyme inhibitor antihypertensive drugs. . 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one Preparation[2] The synthesis methods reported in the literature mainly include: 1. Using a composite…
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Application of 2-(2-difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane_Kain Industrial Additive
Background and Overview 2-(2-Difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane is an organic intermediate commonly used in metal catalysis coupling reaction, Application examples[1-2] Report 1, CN201780052527.0 reported that 2-(2-difluoromethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborane can be used to synthesize compound 6-amino -N-(5-chloro-6-(2-(difluoromethyl)phenyl)pyridin-2-yl)pyridine-2-sulfonamide. This compound is a CF transmembrane conductance regulator (CFTR) corrector. Cystic fibrosis (CF) is caused by loss-of-function mutations in the CF transmembrane conductance regulator (CFTR) protein, which is a cAMP-regulated chloride channel that is mainly…
Preparation and application of 2,4,5,6-tetrafluoroisophthalonitrile_Kain Industrial Additive
Background and overview[1] 2,4,5,6-tetrafluoroisophthalonitrile can be used as a pharmaceutical synthesis intermediate, such as the preparation of dichloruron, which is an insect growth regulator, and the better representative is dichloruron. . Chemuron has the following advantages: 1. Unique mechanism of action, low toxicity to beneficial organisms, easy to degrade, high selectivity, relatively safe, and is an insect growth regulator. 2. High biological activity and low effective…
![2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane](https://www.51dmapa.com/wp-content/themes/iux/thumb.php?src=/images/169938053263419.jpg&w=300&h=193)
2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS: 852227-95-3Chinese name: 4-[3-(4,4,5, 5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenyl Pinacol borate2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2 -DioxaborolaneEnglish name: 4-[3-(4,4,5, 5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenylboronic acid pinacol ester 2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
![4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine](https://www.51dmapa.com/wp-content/themes/iux/thumb.php?src=/images/169938053252047.jpg&w=300&h=193)
4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine
CAS: 852227-95-3Chinese name: 4-[3-(4,4,5, 5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenyl Pinacol borate2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2 -DioxaborolaneEnglish name: 4-[3-(4,4,5, 5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]morpholine3-(morpholino)phenylboronic acid pinacol ester 2-[3-(morpholino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
n,n’-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine and morpholine-2,4,6-trichloro-1,3, Methylated polymer of 5-triazine
CAS: 193098-40-7Chinese name: UV absorber uv3529 n,n’-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexamethylenediamine and morpholine-2,4,6-tri Methylated polymers of chloro-1,3,5-triazines
![4-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidin-2-yl]morpholine](https://www.51dmapa.com/wp-content/themes/iux/thumb.php?src=/images/169936710489563.jpg&w=300&h=193)
4-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidin-2-yl]morpholine
CAS: 485799-04-0Molecular formula: C15H23BN2O3Molecular weight: 290.17Melting point: 135 -139 ℃(lit.)Chinese name: 4-[5-(4,4,5,5-tetramethyl-1,3,2- Dioxaborolan-2-yl)piperidin-2-yl]morpholineEnglish name: 6-(Morpholin-4-yl)pyridine-3-boronic acid pinacol ester1-[5-(4,4,5,5-Tetramethyl-1, 3,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine4-[5-(4,4,5,5-Tetramethyl-1,3 ,2-dioxaborolan-2-yl)pyridin-2-yl]morpholine
4,4′-(Oxydi-2,1-ethylidene)bismorpholine
CAS: 6425-39-4Molecular formula: C12H24N2O3Boiling point: 309℃Chinese name: 4,4′-(Oxydi-2,1-ethylidene)bismorpholineDimorpholino diethyl ether2,2′-Dimorpholino diethyl etherEnglish name: 4,4′-(oxydi-2,1-ethanediyl)bis-MorpholineDimorpholinodiethyl ether 4,4′-(oxydi-2,1-ethanediyl)bis-morpholin4,4′-(oxydi-2,1-ethanediyl)bismorpholine Morpholine,4,4′-(oxydi-2,1-ethanediyl)bis-
