Applications of 3-phenylbut-2-enoic acid_Kain Industrial Additives

overview[1][2] 3-phenylbut-2-enoic acid can be prepared in one step from triethyl phosphonoacetate and phenylacetaldehyde, and can be used to synthesize 2-position disubstituted indolin-3-one compounds. substituted indolin-3-one structures are widely found in biologically active natural product molecules. preparation[1] in a 100 ml two-neck round-bottom flask equipped with a magnetic stir bar, thermometer and condenser, add triethyl phosphonoacetate (1.344 g, 6 mmol), then add thf (20 ml). cool…