N’-bis(2-phenylphosphine-1-naphthoyl)_Kain Industrial Additive

Background and overview[1] (1R,2R)-(+)-1,2-diaminocyclohexane-N,N’-bis(2-phenylphosphine-1-naphthoyl) is an organic phosphine ligand commonly used in transition metal catalyzed reactions. This chiral coordination has proven to be very successful in the amination of butadiene monoepoxides, a type of epoxide and a potential prospect for asymmetric synthesis starting materials (or substrates). Preparation[1] Add 1.90g (5.33mmol) 2-diphenylphosphine-1-naphthoic acid and 42ml dichloromethane into a 100ml round-bottomed flask. After cooling to 0°C, add 1.78g…